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Antibacterial and anti-flaming PA6 composite with metathetically prepared nano AgCl@BaSO

Wei Zhang, Boren Xu, Caihong Gong, Chunwang Yi, Shen Zhang

《化学科学与工程前沿（英文）》 2021年 第15卷 第2期   页码 340-350 doi: 10.1007/s11705-020-1942-9

摘要： In this study, a facile and environmentally friendly method with low energy consumption for preparing nanoscale AgCl and BaSO co-precipitates (AgCl@BaSO co-precipitates) was developed based on the metathetical reaction. Then, the dried co-precipitates were melt-compounded with polyamide 6 (PA6) resins at a specified mass ratio in a twin-screw extruder. The results demonstrated that in the absence of any coating agent or carrier, the nanoparticles of AgCl@BaSO co-precipitates were homogeneously dispersed in the PA6 matrix. Further analysis showed that after the addition of AgCl@BaSO co-precipitates, the antibacterial performance, along with the flame-retardance and anti-dripping characteristics of PA6, was enhanced significantly. In addition, the PA6 composites possessed high spinnability in producing pre-oriented yarn.

关键词： nano AgCl@BaSO4 co-precipitates     antibacterial     flame resistance     PA6 composite     PA6 yarn    

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Preparation and rheological behaviors of PA6/SiO2 nanocompiste

WEI Shanshan, LIU Yuejun, LI Xianggang, HUANG Yugang, WANG Xiayu, ZHANG Ping

《化学科学与工程前沿（英文）》 2007年 第1卷 第4期   页码 332-337 doi: 10.1007/s11705-007-0060-2

摘要： The polyamide 6 (PA6)/SiO nanocomposites were prepared by in situ polymerization and the rheological behaviors were investigated. The morphology of resultant materials was characterized by scanning electron microscopy (SEM) and the rheological behaviors were characterized by capillary rheometer. The results showed that the SiO particle size was around 50 nm and the particles dispersed evenly in PA6 matrix. The nanocomposites were pesudoplastic fluids and the apparent viscosities of nanocomposites increased initially and then decreased with the increase in nano-SiO content at the same temperature. The non-Newtonian indexes of nanocomposites were smaller than those of pure PA6. With the increase in nano-SiO content the apparent viscous activation energies of nanocomposites increased initially and then decreased. The rheological behaviors revealed that there were strong interactions between PA6 macromolecule chains and nano-SiO particles.

关键词： polyamide     temperature     rheological     activation     pesudoplastic    

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Magnetic KIT-6 nano-composite and its amino derivatives as convenient adsorbent for U(VI) sequestration

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 2037-2049 doi: 10.1007/s11705-023-2358-0

摘要： Although mesoporous silica with magnetically hybridized two-dimensional channel structures has been well studied in recent years, it remains a challenge to fabricate the counterpart with macroporous three-dimensional cubic structures since the highly acidic preparation conditions lead to dissolution of magnetic particles. Herein, we successfully prepared magnetic KIT-6 nano-composite and its amino derivatives by bearing acid-resistant iron oxide. The prepared materials exhibited excellent properties for U(VI) ions removal from aqueous solutions under various conditions. The experimental data show that the U(VI) adsorption features fast adsorption kinetics, high adsorption capacity and ideal selectivity toward U(VI). The adsorption process is of spontaneous and endothermic nature and ionic strength independence, and the adsorbents can be easily regenerated by acid treatment. Compared to pristine KIT-6, the introduction of magnetism does not reduce the efficiency of the material to remove U(VI) while exerting its role as a recovery adsorbent. The findings of this work further demonstrate the potential broad application prospects of magnetic hybrid mesoporous silica in radionuclide chelation.

关键词： magnetic nanoparticle     3D mesoporous silica     amino functionalization     adsorption of U(VI)     acid resistance    

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All-inorganic TiO/CsAgBiBr composite as highly efficient photocatalyst under visible light irradiation

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 1925-1936 doi: 10.1007/s11705-023-2344-6

摘要： In recent years, limited photocatalysis efficiency and wide band gap have hindered the application of TiO2 in the field of photocatalysis. A leading star in photocatalysis has been revealed as lead-free Cs2AgBiBr6 double halide perovskite nanocrystals, owing to its strong visible light absorption and tunable band gap. In this work, this photocatalytic process was facilitated by a unique TiO2/Cs2AgBiBr6 composite, which was identified as an S-cheme heterojunction. TiO2/Cs2AgBiBr6 composite was investigated for its structure and photocatalytic behavior. The results showed that when the perovskite dosage is 40%, the photocatalytic rate of TiO2 could be boosted to 0.1369 min–1. This paper discusses and proposes the band gap matching, carrier separation, and photocatalytic mechanism of TiO2/Cs2AgBiBr6 composites, which will facilitate the generation of new ideas for improving TiO2’s photocatalytic performance.

关键词： Cs2AgBiBr6 nanocrystals     visible-light photocatalyst     Cs2AgBiBr6/TiO2 heterojunction    

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Molecular level understanding of CO2 capture in ionic liquid/polyimide composite membrane

Linlin You, Yandong Guo, Yanjing He, Feng Huo, Shaojuan Zeng, Chunshan Li, Xiangping Zhang, Xiaochun Zhang

《化学科学与工程前沿（英文）》 2022年 第16卷 第2期   页码 141-151 doi: 10.1007/s11705-020-2009-7

摘要： Ionic liquid (IL)/polyimide (PI) composite membranes demonstrate promise for use in CO separation applications. However, few studies have focused on the microscopic mechanism of CO in these composite systems, which is important information for designing new membranes. In this work, a series of systems of CO in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide composited with 4,4-(hexafluoroisopropylidene) diphthalic anhydride (6FDA)-based PI, 6FDA-2,3,5,6-tetramethyl-1,4-phenylene-diamine, at different IL concentrations were investigated by all-atom molecular dynamics simulation. The formation of IL regions in PI was found, and the IL regions gradually became continuous channels with increasing IL concentrations. The analysis of the radial distribution functions and hydrogen bond numbers demonstrated that PI had a stronger interaction with cations than anions. However, the hydrogen bonds among PI chains were destroyed by the addition of IL, which was favorable for transporting CO . Furthermore, the self-diffusion coefficient and free energy barrier suggested that the diffusion coefficient of CO decreased with increasing IL concentrations up to 35 wt-% due to the decrease of the fractional free volume of the composite membrane. However, the CO self-diffusion coefficients increased when the IL contents were higher than 35 wt-%, which was attributed to the formation of continuous IL domain that benefitted the transportation of CO .

关键词： carbon dioxide     ionic liquid     6FDA-TeMPD     composite membrane     molecular dynamics simulation    

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A comprehensive analysis of a 3-P (Pa) S spatial parallel manipulator

Yuzhe LIU,Liping WANG,Jun WU,Jinsong WANG

《机械工程前沿（英文）》 2015年 第10卷 第1期   页码 7-19 doi: 10.1007/s11465-015-0324-3

摘要：

In this paper, a novel 3-degree of freedom (3-DOF) spatial parallel kinematic machine (PKM) is analyzed. The manipulator owns three main motions (two rotations and one translation) and three concomitant motions (one rotation and two translations). At first, the structure of this spatial PKM is simplified according to the characteristic of each limb. Secondly, the kinematics model of this spatial PKM is set up. In addition, the relationship between the main motions and concomitant motions is studied. The workspaces respectively based on the outputs and inputs are derived and analyzed. Furthermore, the velocity model is put forward. Two indexes based on the velocity model are employed to investigate the performance of this spatial PKM. At last, the output error model can be obtained and simulated. The comprehensive kinematics analysis in this paper is greatly useful for the future applications of this spatial PKM.

关键词： parallel mechanism     concomitant motions     kinematics     workspaces     error model    

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微波辐射下离子液体［RMIm］PF6（R=P, B, C6）的合成及其电导率研究

何永福

《中国工程科学》 2008年 第10卷 第9期   页码 92-95

摘要： 1－溴己烷)在80 ℃回流加热10 min，可制得咪唑类离子液体的中间体溴代1－丁基－3－甲基咪唑（［BMIm］Br）、溴代1－丙基－3－甲基咪唑（［PMIm］Br）、溴代1－己基－3－甲基咪唑（［C6MIm］Br），进一步与HPF6在室温搅拌反应4 h，制得憎水性的咪唑类离子液体［BMIm］PF6，［PMIm］PF6和［C6MIm］PF6。

关键词： 离子液体     微波辐射     电导率     [BMIm]PF6     [PMIm]PF6     [C6MIm]PF6    

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Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

《医学前沿（英文）》 doi: 10.1007/s11684-023-1044-4

摘要： As of May 3, 2023, the coronavirus disease 2019 (COVID-19) pandemic has resulted in more than 760 million confirmed cases and over 6.9 million deaths. Several patients have developed pneumonia, which can deteriorate into acute respiratory distress syndrome. The primary etiology may be attributed to cytokine storm, which is triggered by the excessive release of proinflammatory cytokines and subsequently leads to immune dysregulation. Considering that high levels of interleukin-6 (IL-6) have been detected in several highly pathogenic coronavirus-infected diseases, such as severe acute respiratory syndrome in 2002, the Middle East respiratory syndrome in 2012, and COVID-19, the IL-6 pathway has emerged as a key in the pathogenesis of this hyperinflammatory state. Thus, we review the history of cytokine storm and the process of targeting IL-6 signaling to elucidate the pivotal role played by tocilizumab in combating COVID-19.

关键词： SARS-CoV-2     COVID-19     cytokine storm     interleukin-6     tocilizumab    

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FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

《医学前沿（英文）》 2023年 第17卷 第4期   页码 714-728 doi: 10.1007/s11684-022-0959-5

摘要： FRMD6, a member of the 4.1 ezrin–radixin–moesin domain-containing protein family, has been reported to inhibit tumor progression in multiple cancers. Here, we demonstrate the involvement of FRMD6 in lung cancer progression. We find that FRMD6 is overexpressed in lung cancer tissues relative to in normal lung tissues. In addition, the enhanced expression of FRMD6 is associated with poor outcomes in patients with lung squamous cell carcinoma (n = 75, P = 0.0054) and lung adenocarcinoma (n = 94, P = 0.0330). Cell migration and proliferation in vitro and tumor formation in vivo are promoted by FRMD6 but are suppressed by the depletion of FRMD6. Mechanistically, FRMD6 interacts and colocalizes with mTOR and S6K, which are the key molecules of the mTOR signaling pathway. FRMD6 markedly enhances the interaction between mTOR and S6K, subsequently increasing the levels of endogenous pS6K and downstream pS6 in lung cancer cells. Furthermore, knocking out FRMD6 inhibits the activation of the mTOR signaling pathway in Frmd6−/− gene KO MEFs and mice. Altogether, our results show that FRMD6 contributes to lung cancer progression by activating the mTOR signaling pathway.

关键词： FRMD6     lung cancer     mTOR pathway    

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1,5-戊二胺的细菌合成及应用 Review

马伟超, 陈可泉, 李艳, 郝宁, 王昕, 欧阳平凯

《工程（英文）》 2017年 第3卷 第3期   页码 308-317 doi: 10.1016/J.ENG.2017.03.012

摘要：

1,5-戊二胺是一种广泛分布于原核和真核生物中的具有多种生物活性的天然多胺，正日益成为一种重要的工业化学品，并在多个领域展现出广泛的应用前景，特别是作为单体用于合成生物基聚酰胺。基于1,5-戊二胺的聚酰胺5X 具有优异的性能和环境友好特性，因而有广泛的应用前景。本文总结了近期关于1,5-戊二胺在细菌中的生物合成、代谢及生理学功能，着重介绍了1,5-戊二胺在大肠杆菌的代谢调控机制。文中还综述了微生物发酵法和全细胞催化法生产1,5-戊二胺的进展及1,5-戊二胺的分离纯化方法。此外，对1,5-戊二胺在生物基聚酰胺合成中的应用进行了总结，并对利用可再生资源生产1,5-戊二胺进行了展望和对以后的研究提出了建议。

关键词： 1     5-戊二胺     代谢     细菌生产     生物基聚酰胺     PA 5X    

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RNA m6A modification and its function in diseases

null

《医学前沿（英文）》 2018年 第12卷 第4期   页码 481-489 doi: 10.1007/s11684-018-0654-8

摘要：

N6-methyladenosine (m6A) is the most common post-transcriptional RNA modification throughout the transcriptome, affecting fundamental aspects of RNA metabolism. m6A modification could be installed by m6A “writers” composed of core catalytic components (METTL3/METTL14/WTAP) and newly defined regulators and removed by m6A “erasers” (FTO and ALKBH5). The function of m6A is executed by m6A “readers” that bind to m6A directly (YTH domain-containing proteins, eIF3 and IGF2BPs) or indirectly (HNRNPA2B1). In the past few years, advances in m6A modulators (“writers,” “erasers,” and “readers”) have remarkably renewed our understanding of the function and regulation of m6A in different cells under normal or disease conditions. However, the mechanism and the regulatory network of m6A are still largely unknown. Moreover, investigations of the m6A physiological roles in human diseases are limited. In this review, we summarize the recent advances in m6A research and highlight the functional relevance and importance of m6A modification in in vitro cell lines, in physiological contexts, and in cancers.

关键词： RNA modification     m6A     immunity     cancer     epigenetics    

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A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodesthe candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors

《医学前沿（英文）》 2023年 第17卷 第3期   页码 458-475 doi: 10.1007/s11684-022-0968-4

摘要： The Ly-6 and uPAR (LU) domain-containing proteins represent a large family of cell-surface markers. In particular, mouse Ly-6A/Sca-1 is a widely used marker for various stem cells; however, its human ortholog is missing. In this study, based on a systematic survey and comparative genomic study of mouse and human LU domain-containing proteins, we identified a previously unannotated human gene encoding the candidate ortholog of mouse Ly-6A/Sca-1. This gene, hereby named LY6A, reversely overlaps with a lncRNA gene in the majority of exonic sequences. We found that LY6A is aberrantly expressed in pituitary tumors, but not in normal pituitary tissues, and may contribute to tumorigenesis. Similar to mouse Ly-6A/Sca-1, human LY6A is also upregulated by interferon, suggesting a conserved transcriptional regulatory mechanism between humans and mice. We cloned the full-length LY6A cDNA, whose encoded protein sequence, domain architecture, and exon‒intron structures are all well conserved with mouse Ly-6A/Sca-1. Ectopic expression of the LY6A protein in cells demonstrates that it acts the same as mouse Ly-6A/Sca-1 in their processing and glycosylphosphatidylinositol anchoring to the cell membrane. Collectively, these studies unveil a novel human gene encoding a candidate biomarker and provide an interesting model gene for studying gene regulatory and evolutionary mechanisms.

关键词： LU domain-containing protein family     novel human gene     LY6A     pituitary tumor     biomarker     nonsynonymous SNP     GPI-anchored protein    

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A rolling 6U parallel mechanism

Zhihuai MIAO, Yanan YAO

《机械工程前沿（英文）》 2011年 第6卷 第1期   页码 96-98 doi: 10.1007/s11465-011-0214-2

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Technological development and engineering applications of novel steel-concrete composite structures

Jianguo NIE, Jiaji WANG, Shuangke GOU, Yaoyu ZHU, Jiansheng FAN

《结构与土木工程前沿（英文）》 2019年 第13卷 第1期   页码 1-14 doi: 10.1007/s11709-019-0514-x

摘要：

In view of China’s development trend of green building and building industrialization, based on the emerging requirements of the structural engineering community, the development and proposition of novel resource-saving high-performance steel-concrete composite structural systems with adequate safety and durability has become a kernel development trend in structural engineering. This paper provides a state of the art review of China’s cutting-edge research and technologies in steel-concrete composite structures in recent years, including the building engineering, the bridge engineering and the special engineering. This paper summarizes the technical principles and applications of the long-span bi-directional composite structures, the long-span composite transfer structures, the comprehensive crack control technique based on uplift-restricted and slip-permitted (URSP) connectors, the steel plate concrete composite (SPCC) strengthen technique, and the innovative composite joints. By improving and revising traditional structure types, the comprehensive superiority of steel-concrete composite structures is well elicited. The research results also indicate that the high-performance steel-concrete composite structures have a promising popularizing prospect in the future.

关键词： high-performance composite structure     bi-directional composite     composite transfer     uplift-restricted and slip-permitted connectors     steel plate concrete composite strengthen    

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抗静电增强尼龙66研制

刘建强

《中国工程科学》 2004年 第6卷 第6期   页码 77-78

摘要：

以阴离子和非离子型抗静电剂组成复合抗静电体系，用玻璃纤维为增强剂，研制成具有良好抗静电和机械性能优良的尼龙66；介绍了抗静电复合体系及玻璃纤维含量对抗静电增强尼龙性能的影响。

关键词： 尼龙66树脂     抗静电     增强剂    

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标题 作者 时间 类型 操作

Antibacterial and anti-flaming PA6 composite with metathetically prepared nano AgCl@BaSO

Wei Zhang, Boren Xu, Caihong Gong, Chunwang Yi, Shen Zhang

期刊论文

Preparation and rheological behaviors of PA6/SiO2 nanocompiste

WEI Shanshan, LIU Yuejun, LI Xianggang, HUANG Yugang, WANG Xiayu, ZHANG Ping

期刊论文

Magnetic KIT-6 nano-composite and its amino derivatives as convenient adsorbent for U(VI) sequestration

期刊论文

All-inorganic TiO/CsAgBiBr composite as highly efficient photocatalyst under visible light irradiation

期刊论文

Molecular level understanding of CO2 capture in ionic liquid/polyimide composite membrane

Linlin You, Yandong Guo, Yanjing He, Feng Huo, Shaojuan Zeng, Chunshan Li, Xiangping Zhang, Xiaochun Zhang

期刊论文

A comprehensive analysis of a 3-P (Pa) S spatial parallel manipulator

Yuzhe LIU,Liping WANG,Jun WU,Jinsong WANG

期刊论文

微波辐射下离子液体［RMIm］PF6（R=P, B, C6）的合成及其电导率研究

何永福

期刊论文

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

期刊论文

FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

期刊论文

1,5-戊二胺的细菌合成及应用

马伟超, 陈可泉, 李艳, 郝宁, 王昕, 欧阳平凯

期刊论文

RNA m6A modification and its function in diseases

null

期刊论文

A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodesthe candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors

期刊论文

A rolling 6U parallel mechanism

Zhihuai MIAO, Yanan YAO

期刊论文

Technological development and engineering applications of novel steel-concrete composite structures

Jianguo NIE, Jiaji WANG, Shuangke GOU, Yaoyu ZHU, Jiansheng FAN

期刊论文

抗静电增强尼龙66研制

刘建强

期刊论文